EXTRACORPOREAL MEMBRANE OXYGENATION IN HIGH-RISK PCI: INSIGHTS FROM CLINICAL CASES

УДК 616.1-089:615.835.32

Authors

  • Irina A. Sukmanova Altai Regional Cardiology Dispensary, Barnaul, Russia; Altai State Medical University, Barnaul, Russia https://orcid.org/0000-0002-3903-0552 Email: vdovinai@yandex.ru
  • Karina S. Smyk Altai State Medical University, Barnaul, Russia Email: kolianova.k@gmail.com
  • Evgeny Yu. Gubarenko Altai Regional Cardiology Dispensary, Barnaul, Russia Email: info@akkd.ru

DOI:

https://doi.org/10.31684/25418475-2024-1-89

Keywords:

STEMI, PCI-high risk, multivessel lesion, mechanical circulatory support, ECMO, a clinical case

Abstract

Introduction. Percutaneous coronary interventions (PCI) have become increasingly intricate, particularly considering patient comorbidities. The simultaneous or staged coronary artery stenting in patients with ST-segment elevation myocardial infarction (STEMI) and multivessel coronary artery disease during the index hospitalization has garnered considerable interest. The utilization of venoarterial extracorporeal membrane oxygenation (VA-ECMO) in PCI has notably increased, serving both as an emergency intervention in acute myocardial infarction (AMI) and in planned PCI to maintain hemodynamics and organ perfusion. The term "high-risk PCI" has been introduced to denote interventions performed using short-term mechanical circulatory support, necessitating a multidisciplinary approach for patient management. Aim. This study aims to investigate the management approaches for high-risk PCI patients using mechanical circulatory support methods. Materials and Methods. A comprehensive literature review on the management of high-risk PCI patients was conducted. Patients with STEMI who underwent LCA trunk stenting at the bifurcation site using ECMO were selected based on the Barnaul ACCD. Results. Data on ECMO use in high-risk PCI are primarily limited to single-center observational studies or individual clinical cases. In the presented cases, ECMO facilitated successful implementation of complex PCI in patients with STEMI and critical stenoses of large coronary arteries. Indications for routine use of mechanical devices during PCI procedures should be individualized, considering potential benefits and complications. In the cases presented, ECMO use during XRD enabled complete revascularization despite acute heart failure and cardiogenic shock, leading to rapid patient stabilization and discharge in satisfactory condition. Conclusions. Managing high-risk PCI patients necessitates a multidisciplinary approach, requiring collaboration among endovascular surgeons, clinical cardiologists, and cardiac surgeons. Critical aspects in the intensive care unit for these patients are not yet fully understood, emphasizing the need to optimize patient condition pre-procedure, manage concurrent diseases, and ensure adequate postoperative care. The synergy between intensive care specialists and cardiologists can significantly impact treatment outcomes in this clinical context.

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Author information

Irina A. Sukmanova,
Altai Regional Cardiology Dispensary, Barnaul, Russia; Altai State Medical University, Barnaul, Russia

Dr. Sci. (Med.), Head of the Department for Patients with Acute Coronary Syndrome, Altai Regional Cardiology Dispensary; Professor, Department of Cardiology and Cardiovascular Surgery with Advanced Training Course, Altai State Medical University, Barnaul.
E-mail: vdovinai@yandex.ru.
https://orcid.org/0000-0002-3903-0552.

Karina S. Smyk,
Altai State Medical University, Barnaul, Russia

Resident Physician, Department of Cardiology and Cardiovascular Surgery with Advanced Training Course, Altai State Medical University, Barnaul.
E-mail: kolianova.k@gmail.com

Evgeny Yu. Gubarenko,
Altai Regional Cardiology Dispensary, Barnaul, Russia

Head of the Department of X-ray Surgical Methods of Diagnosis and Treatment, Altai Regional Cardiology Dispensary, Barnaul.
E-mail: info@akkd.ru

References

  • Waldo S.W., Secemsky E.A., O’Brien C., Kennedy K.F., Pomerantsev E., Sundt T.M. 3rd; McNulty E.J., Scirica B.M., Yeh R.W. Surgical ineligibility and mortality among patients with unprotected left main or multivessel coronary artery disease undergoing percutaneous coronary intervention. Circulation. 2014; 130: 2295-301. https://doi.org/10.1161/circulationaha.114.011541
  • Marc Blaimont, Hugues Trine, Pierre Henin, Romain Courcelle, Yves Laurent, Patrick Van Ruyssevelt, Caroline Lepièce and Vincent Huberlant. Prophylactic ECMO Support during Elective Coronary Percutaneous Interventions in High-Risk Patients: A Single-Center Experience. 04.02.2023; 5332038. https://doi.org/10.1155/2023/5332038
  • Agarwal S., Sud K., Martin J.M., Menon V. Trends in the use of mechanical circulatory support devices in patients presenting with ST-segment elevation myocardial infarction. JACC Cardiovasc Interv. 2015; 8(13): 1772-4. https://doi.org/10.1016/j.jcin.2015.07.015
  • Van den Brink F.S., Magan A.D., Noordzij P.G. et al. Veno-arterial extracorporeal membrane oxygenation in addition to primary PCI in patients presenting with ST-elevation myocardial infarction. Neth Heart J. 2018; 26(2): 76-84. https://doi.org/10.1007/s12471-017-1068-y
  • Shammas N., Roberts S., Early G. Extracorporeal membrane oxygenation for unprotected left main stenting in a patient with totally occluded right coronary artery and severe left ventricular. J Invasive Cardiol. 2002; 14: 756-759.
  • Vainer J., van Ommen V., Maessen J. et al. Elective high-risk percutaneous coronary interventions supported by extracorporeal life support. Am J Cardiol. 2007; 99(6):771-773. https://doi.org/10.1016/j.amjcard.2006.10.034
  • Utilization of Percutaneous Mechanical Circulatory Support Devices in Cardiogenic Shock Complicating Acute Myocardial Infarction and High-Risk Percutaneous Coronary Interventions by Rabea Asleh and Jon R. Resar. 13.08.2019. https://doi.org/10.3390/jcm8081209
  • Go A.S., Mozaffarian D., Roger V.L., Benjamin E.J., Berry J.D., et al. American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Heart disease and stroke statistics-2014 update: a report from the American Heart Association. Circulation. 2014; 129: e28-e292. https://doi.org/10.1161/01.cir.0000441139.02102.80
  • Rihal C.S., Naidu S.S., Givertz M.M., Szeto W.Y., Burke J.A., Kapur N.K. et. al. Society for Cardiovascular Angiography and Interventions (SCAI); Heart Failure Society of America (HFSA); Society for Thoracic Surgeons (STS); American Heart Association (AHA); American College of Cardiology (ACC) 2015. SCAI/ACC/HFSA/STS Clinical expert consensus statement on the use of percutaneous mechanical circulatory support devices in cardiovascular care (Endorsed by the American Heart Association, the Cardiological Society of India, and Sociedad Latino Americana de Cardiologia Intervencion; Affirmation of value by the Canadian Association of Interventional Cardiology-Association Canadienne de Cardiologie d'intervention). J Card Fail. 2015; 21: 499-518. https://doi.org/10.1016/j.cardfail.2015.03.002
  • Craner R.C., Carvajal T., Villablanca P.A., Jahanyar J., Yang E.H., Ramakrishna H. The increasing importance of percutaneous mechanical circulatory support in high-risk transcatheter coronary interventions: an evidence-based analysis. J Cardiothorac Vasc Anesth. 2018; 32: 1507-1524. https://doi.org/10.1053/j.jvca.2017.09.036
  • Guerrero-Miranda C.Y., Hall S.A. Cardiac catheterization and percutaneous intervention procedures on extracorporeal membrane oxygenation support. Ann Cardiothorac Surg. 2019; 8: 123-128. https://doi.org/10.21037/acs.2018.11.08
  • Sianos G., Morel M.A., Kappetein A.P., Morice M.C., Colombo A., Dawkins K., van den Brand M., Van Dyck N., Russell M.E., Mohr F.W., Serruys P.W. The SYNTAX Score: an angiographic tool grading the complexity of coronary artery disease. EuroIntervention. 2005; 1: 219-227.
  • Serruys P.W., Morice M.C., Kappetein A.P., Colombo A., Holmes D.R., Mack M.J., Stahle E., Feldman T.E., van den Brand M., Bass E.J., Van Dyck N., Leadley K., Dawkins K.D., Mohr F.W., SYNTAX Investigators.). Percutaneous coronary intervention versus coronary-artery bypass grafting for severe coronary artery disease. N Engl J Med. 2009; 360: 961-972. https://doi.org/10.1056/nejmoa0804626
  • Burzotta F., Trani C., Doshi S.N., Townend J., van Geuns R.J., Hunziker P., Schieffer B., Karatolios K., Mоller J.E., Ribichini F.L., Schäfer A., Henriques J.P. Impella ventricular support in clinical practice: collaborative viewpoint from a European expert user group. Int J Cardiol. 2015; 201: 684-691. https://doi.org/10.1016/j.ijcard.2015.07.065
  • Tomasello S.D., Boukhris M., Ganyukov V., Galassi A.R., Shukevich D., Haes B., Kochergin N., Tarasov R., Popov V., Barbarash L. Outcome of extracorporeal membrane oxygenation support for complex high-risk elective percutaneous coronary interventions: A single-center experience. Heart Lung. 2015; 44: 309-313. https://doi.org/10.1016/j.hrtlng.2015.03.005
  • Hryniewicz K., Sandoval Y., Samara M., Bennett M., Cabuay B., Chavez I.J., Seatter S., Eckman P., Zimbwa P., Dunn A., Sun B. Percutaneous venoarterial extracorporeal membrane oxygenation for refractory cardiogenic shock is associated with improved short- and long-term survival. ASAIO J. 2016; 62: 397-402. https://doi.org/10.1097/mat.0000000000000378
  • LSO Guidelines for Cardiopulmonary Extracorporeal Life Support Extracorporeal Life Support Organization, Version 1.3. November 2013. Ann Arbor, MI, USA. Available online: http://www.elsonet.org
  • Aissaoui N., El-Banayosy A., Combes A. How to wean a patient from veno-arterial extracorporeal membrane oxygenation. Intensive Care Med. 2015; 41: 902-905. https://doi.org/10.1007/s00134-015-3663-y
  • Cheng R., Hachamovitch R., Kittleson M., Patel J., Arabia F., Moriguchi J., Esmailian F., Azarbal B. Complications of extracorporeal membrane oxygenation for treatment of cardiogenic shock and cardiac arrest: a meta-analysis of 1,866 adult patients. Ann Thorac Surg. 2014; 97: 610-616. https://doi.org/10.1016/j.athoracsur.2013.09.008
  • Yen C.C., Kao C.H., Tsai C.S., Tsai S.H. Identifying the risk factor and prevention of limb ischemia in extracorporeal membrane oxygenation with femoral artery cannulation. Heart Surg Forum. 2018; 21: E018-E022. https://doi.org/10.1532/hsf.1824
  • Makdisi G., Makdisi T., Wang I.W. Use of distal perfusion in peripheral extracorporeal membrane oxygenation. Ann Transl Med. 2017; 5: 103. https://doi.org/10.21037/atm.2017.03.01
  • Keebler M.E., Haddad E.V., Choi C.W., McGrane S., Zalawadiya S., Schlendorf K.H., Brinkley D.M., Danter M.R., Wigger M., Menachem J.N., Shah A., Lindenfeld 2. Venoarterial extracorporeal membrane oxygenation in cardiogenic shock. JACC Heart Fail. 2018; 6: 503-516. https://doi.org/10.1016/j.jchf.2017.11.017
  • Mulder M.M.G., Hassan I., Lancé M. ECMO and anticoagulation: A comprehensive review. Netherlands. J Crit Care. 2018; 26: 6-13.
  • Wong J., Lam J., Mok Y., Lee J. Anticoagulation in extracorporeal membrane oxygenation. JECCM. 2018. https://doi.org/10.21037/jeccm.2018.01.12
  • ELSO Guidelines for Cardiopulmonary Extracorporeal Life Support Extracorporeal Life Support Organization, Version 1.3 November 2013 Ann Arbor, MI, USA. Available online: http://www.elsonet.org
  • Marhong J.D., DeBacker J., Viau-Lapointe J., Munshi L., Del Sorbo L., Burry L., Fan E., Mehta S. Sedation and Mobilization During Venovenous Extracorporeal Membrane Oxygenation for Acute Respiratory Failure: An International Survey. Crit Care Med. 2017; 45: 1893-1899. https://doi.org/10.1097/ccm.0000000000002702
  • Published

    2024-03-25

    How to Cite

    Sukmanova I. A., Smyk K. S., Gubarenko E. Y. EXTRACORPOREAL MEMBRANE OXYGENATION IN HIGH-RISK PCI: INSIGHTS FROM CLINICAL CASES: УДК 616.1-089:615.835.32 // Bulletin of Medical Science, 2024. Vol. 33, № 1. P. 89–98 DOI: 10.31684/25418475-2024-1-89. URL: https://newbmn.asmu.ru/bmn/article/view/668.

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