CRYOSUPERNATANT PLASMA FRACTION IN COMPLEX TREATMENT OF WIDESPREAD SOFT TISSUE PHLEGMON

УДК 616-002.36:616.94:615.382

Authors

DOI:

https://doi.org/10.31684/25418475-2024-1-29

Keywords:

cryoplasma-antiferment complex, freshly frozen plasma, cryosupernatant plasma, sepsis, disseminated intravascular coagulation syndrome, phlegmon

Abstract

The study aimed to compare the outcomes of treating patients with widespread soft tissue phlegmon complicated by sepsis using cryosupernatant plasma and freshly frozen plasma. A total of 61 sepsis-diagnosed patients were involved in the study, divided into two groups. Group 1 received complex treatment with cryosupernatant plasma (CSNP), while group 2 received fresh frozen plasma (FFP). The use of CSNP in the complex treatment of septic patients, as opposed to FFP, resulted in improved treatment outcomes, reduced progression of multiple organ failure, prevention of thrombotic and thromboembolic complications, decreased mortality, and faster normalization of hemocoagulation and fibrinolysis system indicators.

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Evgeny A. Tseimakh,
Altai State Medical University, Barnaul, Russia

Dr. Sci. (Med.), Professor, Head of the Department of General Surgery, Operative Surgery and Topographic Anatomy, Altai State Medical University, Barnaul.
E-mail: yea220257@mail.ru
https://orcid.org/0000-0002-0628-8688

Victor Yu. Zinchenko,
Altai State Medical University, Barnaul, Russia; City Hospital No. 8, Barnaul, Russia

Cand. Sci. (Med.), Associate Professor, Department of General Surgery, Operative Surgery and Topographic Anatomy, Altai State Medical University; Surgeon, Department of Purulent Surgery, City Hospital No. 8, Barnaul.
E-mail: jurevich1987@mail.ru
https://orcid.org/0000-0001-9475-2809

Olga Yu. Lavrinenko,
City Hospital No. 8, Barnaul, Russia

Chief Physician, City Hospital No. 8, Barnaul.
E-mail: olga-uka1977@mail.ru
https://orcid.org/0000-0003-2022-5402

Alexander V. Kalashnikov,
Altai State Medical University, Barnaul, Russia; City Hospital No. 8, Barnaul, Russia

Head of Purulent Surgery Department, City Hospital No. 8, Barnaul; Assistant, Department of General Surgery, Operative Surgery and Topographic Anatomy, Altai State Medical University.
E-mail: kalashnikov.a.v22@mail.ru
https://orcid.org/0000-0001-5239-7327

Elena A. Shalabod,
City Hospital No. 8, Barnaul, Russia

Head of Clinical Laboratory Diagnostics Department, City Hospital No. 8, Barnaul.
E-mail: lena.alekseevna.456@mail.ru

References

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    Published

    2024-03-25

    How to Cite

    Tseimakh E. A., Zinchenko V. Y., Lavrinenko O. Y., Kalashnikov A. V., Shalabod E. A. CRYOSUPERNATANT PLASMA FRACTION IN COMPLEX TREATMENT OF WIDESPREAD SOFT TISSUE PHLEGMON: УДК 616-002.36:616.94:615.382 // Bulletin of Medical Science, 2024. Vol. 33, № 1. P. 29–38 DOI: 10.31684/25418475-2024-1-29. URL: https://newbmn.asmu.ru/bmn/article/view/661.

    Issue

    Vol. 33 No. 1 (2024): Bulletin of Medical Science

    Section

    ORIGINAL PAPERS

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    This work is licensed under a Creative Commons Attribution 4.0 International License.

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